Permanent Staff

Dr. Elisabeth Davioud-Charvet    
Directeur de Recherches CNRS (DR2)
Director of the laboratory of Bioorganic & Medicinal Chemistry


Telephone : +33 (0)3.68.85.26.20
Fax : +33 (0)3.68.85.27.42
E-mail : elisabeth.davioud@unistra.fr

Dr. Mourad El Habiri
Chargé de Recherche CNRS (CR1)
Leader of the physico-electrochemistry core facilities


Telephone : +33 (0)3.68.85.26.85
E-mail : elhabiri@unistra.fr

Current members

Post Doctorant

Dr. Don-Antoine LANFRANCHI
Post-Doc, since 2009
Total synthesis - Enantioselective Diels-Alder reaction - 1,4-Naphthoquinones - Low-weight Starting-Blocks - Salvinorin A
lanfranchi@unistra.fr
 
Dr. Olga BLANK
Post-Doc, since 2010
Methylene blue
 
Dr. Didier BELORGEY
Post-Doc, since 2011
Biochemistry, enzymology
dbelorgey@unistra.fr
 
Dr. Karène URGIN
Post-Doc, since 2011
Organic chemistry, electrochemistry
 
PhD Students

Thibault GENDRON
PhD student, from october 2009 to october 2012
Design and synthesis of bis(Michael acceptors) and prodrugs as dithiol reagents and antitrypanosomal drug-candidates
thibault.gendron@etu.unistra.fr
 
Elena CESAR RODO
Joined PhD thesis with Madrid University, from october 2010 to october 2013
Total synthesis of 1,4-naphtoquinones and aza-analogues interfering with parasitic glutathione reductases
elena.cesar-rodo@ecpm.u-strasbg.fr
 
Katharina EHRHARDT
Joined PhD thesis with Heidelberg University, from october 2010 to october 2013
Antimalarial 1,4-naphthoquinones: drug resistance & combinations, parasite imaging
K.Ehrhardt@stud.uni-heidelberg.de
 
Xavier MARTIN BENLLOCH
PhD student, from october 2011 to october 2014
Synthesis and physico-chemical study of an antiviral flavonoid lead: multidisciplinary approach to unravel the mode of action targeting virion entry
xavier.martin-benlloch@etu.unistra.fr
 
Alexandra NOVODOMSKA
Joined PhD thesis with Heidelberg University, from september 2008 to october 2012
Flavones - Redox-cyclers - Pd-catalyzed reactions - Mechanism of action studies - Physico-Chemistry

Former members

Dr. Laure JOHANN
Joined PhD thesis with Heidelberg University - finished in 2011
Synthesis and mechanism of 1,4-naphthoquinones as turncoat inhibitors of disulfide reductases affecting the redox equilibrium of schistosomes and malaria parasites
Current position : leader position in Research & Development, Clariant, Basel
Dr. Bachir BENSENANE
Joined PhD thesis (IPHC, UMR 7178 CNRS/UdS, ECPM – Es Sénia University, Algeria) - finished in september 2011
Training period in the physico(bio)chemistry group from december 2010 to february 2011
Synthèse de récepteurs macrocycliques fluorescents et propriétés complexantes de métaux lourds et de lanthanides
Current position : Assistant-Professor Oran Es-Sénia University (Algeria)
 
Dr. Nicole WENZEL
PhD Thesis, Université d’Heidelberg, magna cum laude - finished in 2009
Synthesis and Mechanism of Antiparasitic Mannich Base Derivatives Affecting the Redox Equilibrium of Trypanosomes and Malaria Parasites
Current position : leader position in Research & Development, BASF, Ludwigshafen
 
Dr. Tobias MULLER
PhD Thesis, Université d’Heidelberg, magna cum laude - finished in 2008
Novel 1,4-Naphthoquinones as Inhibitors of Human and Plasmodial Glutathione Reductase and as Antimalarial Drugs. Synthesis, Enzymology and Activity Evaluation
Current position : leader position in Research & Development, Roche, Mannheim
 
Dr. Winzer Andreas
Thesis in Medicine, University of Heidelberg, magna cum laude - finished in 2007
Naphthochinone als Sabotage-Inhibitoren der glutathionreduktasen aus malaria-infizierten Erhythrozyten – Kinetische und kristallographische Analyse neuartiger Substanzen
Current position : Physician at the Hospital
 
Dr. Wolfgang FRIEBOLIN
Post-Doctorant from january 2005 to december 2005
Synthesis of dual prodrugs derived from fluoromethyl naphthoquinones and Mannich bases to target malarial NADPH-dependent disulfide reductases
Current position : High-School teacher in chemistry and physics, Directeur des Etudes de Chimie (Professeur-Instructeur)
 
Dr. Holger BAUER
Post-Doctorant, from june 2003 to january 2005
Synthesis of fluoromethyl naphthoquinones and of trypanocidal Mannich bases
Current position : leader position in Research & Development, Merck, Darmstadt